E2F-1 Mouse Monoclonal Antibody
产品名称： E2F-1 Mouse Monoclonal Antibody
英文名称： E2F-1 Mouse Monoclonal Antibody
产品编号： K000152M
产品价格： null
产品产地： 北京市通州区马驹桥
品牌商标： solarbio
更新时间： 2025-05-30T15:53:18
使用范围： WB IF IP
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
- 电话 : 178****1073 点击查看
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- 邮箱 : 3193328036@qq.com
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Anti-E2F-1 Monoclonal Antibody
品牌：solarbio | 货号：K000152M
英文名称
Anti-E2F-1 Monoclonal Antibody
宿主
Mouse
别名
E2F-1;RBAP1;RBBP3;RBP3
应用
WB IF IP
稀释比例
WB 1:500. ICC 1:100.
交叉反应
Human Rat
蛋白分子量
70kDa
Gene ID
1869
保存
Store at -20°C. Avoid freeze / thaw cycles.
储存液
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法
Affinity purification
亚型
IgG2b
免疫原
Purified recombinant human E2F-1 protein fragments expressed in E.coli.
性状
液体
Public Immunogen Range
Purified recombinant human E2F-1 protein fragments expressed in E.coli.
Subcellular Locations
Nucleus
Swiss Prot
Q01094
克隆号
4G8-2C2-C12
克隆类型
Monoclonal Antibody
背景资料
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.
| 英文名称 | Anti-E2F-1 Monoclonal Antibody |
|---|---|
| 宿主 | Mouse |
| 别名 | E2F-1;RBAP1;RBBP3;RBP3 |
| 应用 | WB IF IP |
| 稀释比例 | WB 1:500. ICC 1:100. |
| 交叉反应 | Human Rat |
| 蛋白分子量 | 70kDa |
| Gene ID | 1869 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG2b |
| 免疫原 | Purified recombinant human E2F-1 protein fragments expressed in E.coli. |
| 性状 | 液体 |
| Public Immunogen Range | Purified recombinant human E2F-1 protein fragments expressed in E.coli. |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q01094 |
| 克隆号 | 4G8-2C2-C12 |
| 克隆类型 | Monoclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. |