Anti-CDK4 Monoclonal Antibody-抗体-抗体-生物在线

Anti-CDK4 Monoclonal Antibody

商家询价

产品名称： Anti-CDK4 Monoclonal Antibody

英文名称： Anti-CDK4 Monoclonal Antibody

产品编号： K000051M

产品价格： null

产品产地：北京

品牌商标： Solarbio

更新时间： 2025-05-30T15:53:18

使用范围： WB

北京索莱宝科技有限公司

联系人 : 索莱宝-龚思雨
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产品详情

Anti-CDK4 Monoclonal Antibody
品牌：solarbio | 货号：K000051M

英文名称 Anti-CDK4 Monoclonal Antibody
别名 CMM3;PSK-J3
应用 WB
稀释比例 WB 1:1000.
交叉反应 Human Mouse Rat
蛋白分子量 33kDa
Gene ID 1019
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG1
免疫原 Purified recombinant human CDK4 protein fragments expressed in E.coli.
性状 液体
Public Immunogen Range Purified recombinant human CDK4 protein fragments expressed in E.coli.
Subcellular Locations Cytoplasm Membrane Nucleus
Swiss Prot P11802
克隆号 3F9-B12-C8
克隆类型 Monoclonal Antibody
背景资料 The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.

英文名称	Anti-CDK4 Monoclonal Antibody
别名	CMM3;PSK-J3
应用	WB
稀释比例	WB 1:1000.
交叉反应	Human Mouse Rat
蛋白分子量	33kDa
Gene ID	1019
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG1
免疫原	Purified recombinant human CDK4 protein fragments expressed in E.coli.
性状	液体
Public Immunogen Range	Purified recombinant human CDK4 protein fragments expressed in E.coli.
Subcellular Locations	Cytoplasm Membrane Nucleus
Swiss Prot	P11802
克隆号	3F9-B12-C8
克隆类型	Monoclonal Antibody
背景资料	The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.